» Tridek-One raises 16 million euros to develop first-in-class anti-checkpoint immunotherapies MyPharma Editions

Tridek-One, a biotechnology start-up specializing within the analysis and improvement of CD31 agonists to revive immune stability, has simply introduced a fundraising of 16 million euros throughout a funding spherical led by the Swiss Pureos BioVentures. This operation is being carried out alongside newcomers Bpifrance, by means of its InnoBio2 fund, and Bioqube Ventures (Belgium), with the participation of historic traders AdBio companions and Creation Life Sciences. The funds will first be used to establish drug candidates to be developed in opposition to autoimmune illnesses, to conduct regulatory preclinical research and to construction the corporate. In 2019, Tridek-One had raised 3 million euros throughout a primary funding spherical with AdBio companions (France) and Creation Life Sciences (United Kingdom).

Based in 2018 by Dr Giuseppina Caligiuri and Pr Antonino Nicoletti, researchers in INSERM unit 1148 (Paris), with the assist of AdBio companions as historic investor, Tridek-One is creating a CD31 agonist strategy meant to modulate immune activation for the therapy of autoimmune illnesses.

Tridek-One has additionally appointed Laurence de Schoulepnikoff as CEO, efficient July 1, 2022. An knowledgeable within the pharmaceutical and biotech trade, Laurence de Schoulepnikoff has in depth expertise in transactions and R&D actions within the subject. life sciences. She has labored for biotech start-ups funded by enterprise capital corporations and for mid-sized personal firms, in addition to multinationals. Previous to becoming a member of Tridek-One, she was Director of Enterprise Improvement and Director of Operations at AMAL Therapeutics, a Swiss biotechnology firm specializing in therapeutic oncology vaccines. AMAL was acquired in 2019 by Boehringer Ingelheim. At Tridek-One, Ms. de Schoulepnikoff can be in command of technique and improvement, in addition to the consolidation of the corporate’s construction.

“I’m delighted to hitch Tridek-One and grateful for this chance to guide the corporate as we enter a strategic interval the place we anticipate to achieve a number of main preclinical milestones and construct a number one biotech for the therapy of autoimmune illnesses,” says Laurence de Schoulepnikoff, CEO of Tridek-One.

Following this funding spherical, Klaus Breiner from Pureos Bioventures and Benoit Barteau from Bpifrance be part of the corporate’s board of administrators, as does Erik van den Berg, CEO of AM-Pharma, who turns into its unbiased chairman.

“I’m delighted to hitch Tridek-One as Chairman, as the corporate grows stronger with an skilled group and with the assist of a syndicate of worldwide traders who’ve chosen to belief many years of analysis carried out by the group of Dr Giuseppina Caligiuri and Pr Antonino Nicoletti”, provides Erik van den Berg.

“There’s nonetheless a big unmet medical want in lots of autoimmune illnesses. The agonist strategy of inhibitory receptors of the immune system, comparable to CD31, might rebalance the immune system with out a systemic immunosuppressive impact. We’re delighted to develop this idea with Tridek-One and to assist them of their analysis and preclinical phases,” explains Klaus Breiner, Affiliate Director at Pureos Bioventures.

“AdBio companions was a founding investor of Tridek-One in 2018, we have been then joined by Creation Life Sciences. We’re delighted to welcome new traders who strongly consider in Tridek-One’s disruptive innovation. This confirms our preliminary alternative as an entrepreneur-investor”, declares Alain Huriez, president of AdBio companions.

“Being supported by traders who consider within the Tridek-One undertaking is a implausible alternative. This can permit us to speed up our work to establish and develop first-in-class immune checkpoint agonists able to controlling severe inflammatory illnesses”, conclude Dr. Giuseppina Caligiuri and Prof. Antonino Nicoletti, Scientific Founders from Tridek-One.

Supply and visible: Tridek-On